nCells are full of irreducibly
complex (IC) devices - little protein machines that work only if all the parts (proteins) are present and arranged correctly
nNatural selection does not provide a plausible mechanism to get from nothing to the collection of parts necessary to run a number of irreducibly complex
protein machines vital to living cells
nEvolution of these protein machines must occur in single big steps, not gradually, as to be selected a protein must be functional in some way. Each protein machine is fairly complex, thus evolution in a single step seems unlikely